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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.
Lancet. 2015;:ePub - PMID: 26490195
Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
Mol Psychiatry. 2015;:ePub - PMID: 26503763
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.
Nat Genet. 2015;:ePub - PMID: 26523775
Genetic effect of chemotherapy exposure in children of testicular cancer survivors.
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Abundant contribution of short tandem repeats to gene expression variation in humans.
Nat Genet. 2015;:ePub - PMID: 26642241
Quantifying prion disease penetrance using large population control cohorts.
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Schizophrenia risk from complex variation of complement component 4.
Nature. 2016;:ePub - PMID: 26814963
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.
Nat Neurosci. 2016;:ePub - PMID: 26854805
A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis.
J Clin Invest. 2016;:ePub - PMID: 26901816
A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis.
J Clin Invest. 2016;:ePub - PMID: 26927868
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.
Nat Neurosci. 2016;:ePub - PMID: 26974950
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.
Nat Genet. 2016;:ePub - PMID: 26998691
Survey of variation in human transcription factors reveals prevalent DNA binding changes.
Science. 2016;351(6280):1450-4 - PMID: 27013732
The statistical properties of gene-set analysis.
Nat Rev Genet. 2016;:ePub - PMID: 27070863
The Weighting is the Hardest Part: On the Behavior of the Likelihood Ratio Test and the Score Test Under a Data-Driven Weighting Scheme in Sequenced Samples.
Twin Res Hum Genet. 2017;:1-11 - PMID: 28238293
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Mosaic mutations in blood DNA sequence are associated with solid tumor cancers.
NPJ Genom Med. 2017;2:22 - PMID: 29263833 - PMCID: PMC5677955
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Sci Data. 2017;4:170179 - PMID: 29257133
An Unexpectedly Complex Architecture for Skin Pigmentation in Africans.
Cell. 2017;171(6):1340-1353.e14 - PMID: 29195075
Whole genome sequencing in psychiatric disorders: the WGSPD consortium.
Nat Neurosci. 2017;20(12):1661-1668 - PMID: 29184211
Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection.
Sci Rep. 2017;7(1):15843 - PMID: 29158528
Corrigendum: High-throughput discovery of novel developmental phenotypes.
Nature. 2017;551(7680):398 - PMID: 29144450
Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease.
Proc Natl Acad Sci U S A. 2017;114(43):11392-11397 - PMID: 29073062
Fine-Scale Genetic Structure in Finland.
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Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.
Nat Genet. 2017;:ePub - PMID: 28892061
Discovery of stimulation-responsive immune enhancers with CRISPR activation.
Nature. 2017;:ePub - PMID: 28854172
Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia.
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Polygenic risk for schizophrenia and neurocognitive performance in patients with schizophrenia.
Genes Brain Behav. 2017;:ePub - PMID: 28719030
Anti-high mobility group box-1 (HMGB1) antibody attenuates kidney damage following experimental crush injury and the possible role of the tumor necrosis factor-α and c-Jun N-terminal kinase pathway.
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Integrative Genetic and Epigenetic Analysis Uncovers Regulatory Mechanisms of Autoimmune Disease.
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Effects of Lactobacillus rhamnosus GG on the maturation and differentiation of dendritic cells in rotavirus-infected mice.
Benef Microbes. 2017;:1-12 - PMID: 28670908
Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.
Nat Neurosci. 2017;:ePub - PMID: 28671696
Fine-mapping inflammatory bowel disease loci to single-variant resolution.
Nature. 2017;:ePub - PMID: 28658209
Quantifying the genetic correlation between multiple cancer types.
Cancer Epidemiol Biomarkers Prev. 2017;:ePub - PMID: 28637796
Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.
Neuron. 2017;94(6):1101-1111.e7 - PMID: 28641109
Corrigendum: SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome.
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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.
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De Novo Coding Variants Are Strongly Associated with Tourette Disorder.
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Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity.
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Overweight or about right? A norm comparison explanation of perceived weight status.
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Phenome-wide heritability analysis of the UK Biobank.
PLoS Genet. 2017;13(4):e1006711 - PMID: 28388634
Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations.
Am J Hum Genet. 2017;:ePub - PMID: 28366442
Estimating the selective effects of heterozygous protein-truncating variants from human exome data.
Nat Genet. 2017;:ePub - PMID: 28369035
A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
Diabetes. 2017;:ePub - PMID: 28341696
Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues.
Am J Hum Genet. 2017;:ePub - PMID: 28343628
Large-Scale trans-eQTLs Affect Hundreds of Transcripts and Mediate Patterns of Transcriptional Co-regulation.
Am J Hum Genet. 2017;:ePub - PMID: 28285767
Identification of Developmental and Behavioral Markers Associated With Genetic Abnormalities in Autism Spectrum Disorder.
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A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.
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Analysis of protein-coding genetic variation in 60,706 humans.
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