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Magnusson PK, Almqvist C, Rahman I, Ganna A, Viktorin A, Walum H, Halldner L, Lundström S, Ullén F, Långström N, Larsson H, Nyman A, Gumpert CH, Råstam M, Anckarsäter H, Cnattingius S, Johannesson M, Ingelsson E, Klareskog L, de Faire U, Pedersen NL, Lichtenstein P
The Swedish Twin Registry: establishment of a biobank and other recent developments.
Twin Res Hum Genet. 2012;16(1):317-29 - PMID: 23137839
Ganna A, Reilly M, de Faire U, Pedersen N, Magnusson P, Ingelsson E
Risk prediction measures for case-cohort and nested case-control designs: an application to cardiovascular disease.
Am J Epidemiol. 2012;175(7):715-24 - PMID: 22396388 - PMCID: PMC3324433
Gymrek M
PyBamView: a browser-based application for viewing short read alignments.
Bioinformatics. 2014;30(23):3405-7 - PMID: 25147359
Riggi N, Knoechel B, Gillespie SM, Rheinbay E, Boulay G, Suvà ML, Rossetti NE, Boonseng WE, Oksuz O, Cook EB, Formey A, Patel A, Gymrek M, Thapar V, Deshpande V, Ting DT, Hornicek FJ, Nielsen GP, Stamenkovic I, Aryee MJ, Bernstein BE, Rivera MN
EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma.
Cancer Cell. 2014;26(5):668-81 - PMID: 25453903 - PMCID: PMC4492343
Breker M, Gymrek M, Moldavski O, Schuldiner M
LoQAtE--Localization and Quantitation ATlas of the yeast proteomE. A new tool for multiparametric dissection of single-protein behavior in response to biological perturbations in yeast.
Nucleic Acids Res. 2013;42(Database issue):D726-30 - PMID: 24150937 - PMCID: PMC3965041
Willems T, Gymrek M, Highnam G, , Mittelman D, Erlich Y
The landscape of human STR variation.
Genome Res. 2014;24(11):1894-904 - PMID: 25135957 - PMCID: PMC4216929
Zielinski D, Markus B, Sheikh M, Gymrek M, Chu C, Zaks M, Srinivasan B, Hoffman JD, Aizenbud D, Erlich Y
OTX2 duplication is implicated in hemifacial microsomia.
PLoS One. 2014;9(5):e96788 - PMID: 24816892 - PMCID: PMC4016008
Breker M, Gymrek M, Schuldiner M
A novel single-cell screening platform reveals proteome plasticity during yeast stress responses.
J Cell Biol. 2013;200(6):839-50 - PMID: 23509072 - PMCID: PMC3601363
Gymrek M, McGuire AL, Golan D, Halperin E, Erlich Y
Identifying personal genomes by surname inference.
Science. 2013;339(6117):321-4 - PMID: 23329047
Gymrek M, Erlich Y
Profiling short tandem repeats from short reads.
Methods Mol Biol. 2013;1038:113-35 - PMID: 23872972
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.
Cell. 2012;151(6):1185-99 - PMID: 23217706 - PMCID: PMC3526953
Nadler-Holly M, Breker M, Gruber R, Azia A, Gymrek M, Eisenstein M, Willison KR, Schuldiner M, Horovitz A
Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich proteins revealed by high-throughput microscopy analysis.
Proc Natl Acad Sci U S A. 2012;109(46):18833-8 - PMID: 23112166 - PMCID: PMC3503220
Gymrek M, Golan D, Rosset S, Erlich Y
lobSTR: A short tandem repeat profiler for personal genomes.
Genome Res. 2012;22(6):1154-62 - PMID: 22522390 - PMCID: PMC3371701
Zielinski D, Gymrek M, Erlich Y
Back to the family: a renewed approach to rare variant studies.
Genome Med. 2012;4(12):97 - PMID: 23253160 - PMCID: PMC3580437
Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, Bernstein BE
Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells.
Cell. 2011;147(7):1628-39 - PMID: 22196736 - PMCID: PMC3312319
Gymrek M, Erlich Y
Using DNA sequencers as stethoscopes.
Genome Med. 2011;3(11):73 - PMID: 22103962 - PMCID: PMC3308028
Naegle KM, Gymrek M, Joughin BA, Wagner JP, Welsch RE, Yaffe MB, Lauffenburger DA, White FM
PTMScout, a Web resource for analysis of high throughput post-translational proteomics studies.
Mol Cell Proteomics. 2010;9(11):2558-70 - PMID: 20631208 - PMCID: PMC2984232
Ozsolak F, Goren A, Gymrek M, Guttman M, Regev A, Bernstein BE, Milos PM
Digital transcriptome profiling from attomole-level RNA samples.
Genome Res. 2010;20(4):519-25 - PMID: 20133332 - PMCID: PMC2847755
Goren A, Ozsolak F, Shoresh N, Ku M, Adli M, Hart C, Gymrek M, Zuk O, Regev A, Milos PM, Bernstein BE
Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.
Nat Methods. 2009;7(1):47-9 - PMID: 19946276 - PMCID: PMC2862482
Meyer WK, Zhang S, Hayakawa S, Imai H, Przeworski M
The convergent evolution of blue iris pigmentation in primates took distinct molecular paths.
Am J Phys Anthropol. 2013;151(3):398-407 - PMID: 23640739 - PMCID: PMC3746105
Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E, , , Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL, ,
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
Am J Hum Genet. 2014;95(5):535-52 - PMID: 25439723 - PMCID: PMC4225595
Ripke S, O'Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, Bergen SE, Collins AL, Crowley JJ, Fromer M, Kim Y, Lee SH, Magnusson PK, Sanchez N, Stahl EA, Williams S, Wray NR, Xia K, Bettella F, Borglum AD, Bulik-Sullivan BK, Cormican P, Craddock N, de Leeuw C, Durmishi N, Gill M, Golimbet V, Hamshere ML, Holmans P, Hougaard DM, Kendler KS, Lin K, Morris DW, Mors O, Mortensen PB, Neale BM, O'Neill FA, Owen MJ, Milovancevic MP, Posthuma D, Powell J, Richards AL, Riley BP, Ruderfer D, Rujescu D, Sigurdsson E, Silagadze T, Smit AB, Stefansson H, Steinberg S, Suvisaari J, Tosato S, Verhage M, Walters JT, , Levinson DF, Gejman PV, Kendler KS, Laurent C, Mowry BJ, O'Donovan MC, Owen MJ, Pulver AE, Riley BP, Schwab SG, Wildenauer DB, Dudbridge F, Holmans P, Shi J, Albus M, Alexander M, Campion D, Cohen D, Dikeos D, Duan J, Eichhammer P, Godard S, Hansen M, Lerer FB, Liang KY, Maier W, Mallet J, Nertney DA, Nestadt G, Norton N, O'Neill FA, Papadimitriou GN, Ribble R, Sanders AR, Silverman JM, Walsh D, Williams NM, Wormley B, , Arranz MJ, Bakker S, Bender S, Bramon E, Collier D, Crespo-Facorro B, Hall J, Iyegbe C, Jablensky A, Kahn RS, Kalaydjieva L, Lawrie S, Lewis CM, Lin K, Linszen DH, Mata I, McIntosh A, Murray RM, Ophoff RA, Powell J, Rujescu D, Van Os J, Walshe M, Weisbrod M, Wiersma D, , Donnelly P, Barroso I, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin AP, Deloukas P, Duncanson A, Jankowski J, Markus HS, Mathew CG, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Wood NW, Spencer CC, Band G, Bellenguez C, Freeman C, Hellenthal G, Giannoulatou E, Pirinen M, Pearson RD, Strange A, Su Z, Vukcevic D, Donnelly P, Langford C, Hunt SE, Edkins S, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Gray E, Hammond N, Jayakumar A, McCann OT, Liddle J, Potter SC, Ravindrarajah R, Ricketts M, Tashakkori-Ghanbaria A, Waller MJ, Weston P, Widaa S, Whittaker P, Barroso I, Deloukas P, Mathew CG, Blackwell JM, Brown MA, Corvin AP, McCarthy MI, Spencer CC, Bramon E, Corvin AP, O'Donovan MC, Stefansson K, Scolnick E, Purcell S, McCarroll SA, Sklar P, Hultman CM, Sullivan PF
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
Nat Genet. 2013;45(10):1150-9 - PMID: 23974872 - PMCID: PMC3827979
Ripke S, Neale BM, Corvin A, Walters JT, Farh KH, Holmans PA, Lee P, Bulik-Sullivan B, Collier DA, Huang H, Pers TH, Agartz I, Agerbo E, Albus M, Alexander M, Amin F, Bacanu SA, Begemann M, Belliveau RA Jr, Bene J, Bergen SE, Bevilacqua E, Bigdeli TB, Black DW, Bruggeman R, Buccola NG, Buckner RL, Byerley W, Cahn W, Cai G, Campion D, Cantor RM, Carr VJ, Carrera N, Catts SV, Chambert KD, Chan RC, Chen RY, Chen EY, Cheng W, Cheung EF, Chong SA, Cloninger CR, Cohen D, Cohen N, Cormican P, Craddock N, Crowley JJ, Curtis D, Davidson M, Davis KL, Degenhardt F, Del Favero J, Demontis D, Dikeos D, Dinan T, Djurovic S, Donohoe G, Drapeau E, Duan J, Dudbridge F, Durmishi N, Eichhammer P, Eriksson J, Escott-Price V, Essioux L, Fanous AH, Farrell MS, Frank J, Franke L, Freedman R, Freimer NB, Friedl M, Friedman JI, Fromer M, Genovese G, Georgieva L, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, Golimbet V, Gopal S, Gratten J, de Haan L, Hammer C, Hamshere ML, Hansen M, Hansen T, Haroutunian V, Hartmann AM, Henskens FA, Herms S, Hirschhorn JN, Hoffmann P, Hofman A, Hollegaard MV, Hougaard DM, Ikeda M, Joa I, Julià A, Kahn RS, Kalaydjieva L, Karachanak-Yankova S, Karjalainen J, Kavanagh D, Keller MC, Kennedy JL, Khrunin A, Kim Y, Klovins J, Knowles JA, Konte B, Kucinskas V, Ausrele Kucinskiene Z, Kuzelova-Ptackova H, Kähler AK, Laurent C, Keong JL, Lee SH, Legge SE, Lerer B, Li M, Li T, Liang KY, Lieberman J, Limborska S, Loughland CM, Lubinski J, Lönnqvist J, Macek M Jr, Magnusson PK, Maher BS, Maier W, Mallet J, Marsal S, Mattheisen M, Mattingsdal M, McCarley RW, McDonald C, McIntosh AM, Meier S, Meijer CJ, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mokrab Y, Morris DW, Mors O, Murphy KC, Murray RM, Myin-Germeys I, Müller-Myhsok B, Nelis M, Nenadic I, Nertney DA, Nestadt G, Nicodemus KK, Nikitina-Zake L, Nisenbaum L, Nordin A, O'Callaghan E, O'Dushlaine C, O'Neill FA, Oh SY, Olincy A, Olsen L, Van Os J, Pantelis C, Papadimitriou GN, Papiol S, Parkhomenko E, Pato MT, Paunio T, Pejovic-Milovancevic M, Perkins DO, Pietiläinen O, Pimm J, Pocklington AJ, Powell J, Price A, Pulver AE, Purcell SM, Quested D, Rasmussen HB, Reichenberg A, Reimers MA, Richards AL, Roffman JL, Roussos P, Ruderfer DM, Salomaa V, Sanders AR, Schall U, Schubert CR, Schulze TG, Schwab SG, Scolnick EM, Scott RJ, Seidman LJ, Shi J, Sigurdsson E, Silagadze T, Silverman JM, Sim K, Slominsky P, Smoller JW, So HC, Spencer CA, Stahl EA, Stefansson H, Steinberg S, Stogmann E, Straub RE, Strengman E, Strohmaier J, Stroup TS, Subramaniam M, Suvisaari J, Svrakic DM, Szatkiewicz JP, Söderman E, Thirumalai S, Toncheva D, Tosato S, Veijola J, Waddington J, Walsh D, Wang D, Wang Q, Webb BT, Weiser M, Wildenauer DB, Williams NM, Williams S, Witt SH, Wolen AR, Wong EH, Wormley BK, Xi HS, Zai CC, Zheng X, Zimprich F, Wray NR, Stefansson K, Visscher PM, Adolfsson R, Andreassen OA, Blackwood DH, Bramon E, Buxbaum JD, Børglum AD, Cichon S, Darvasi A, Domenici E, Ehrenreich H, Esko T, Gejman PV, Gill M, Gurling H, Hultman CM, Iwata N, Jablensky AV, Jönsson EG, Kendler KS, Kirov G, Knight J, Lencz T, Levinson DF, Li QS, Liu J, Malhotra AK, McCarroll SA, McQuillin A, Moran JL, Mortensen PB, Mowry BJ, Nöthen MM, Ophoff RA, Owen MJ, Palotie A, Pato CN, Petryshen TL, Posthuma D, Rietschel M, Riley BP, Rujescu D, Sham PC, Sklar P, St Clair D, Weinberger DR, Wendland JR, Werge T, Daly MJ, Sullivan PF, O'Donovan MC
Biological insights from 108 schizophrenia-associated genetic loci.
Nature. 2014;511(7510):421-7 - PMID: 25056061 - PMCID: PMC4112379
Ganna A, Lee D, Ingelsson E, Pawitan Y
Rediscovery rate estimation for assessing the validation of significant findings in high-throughput studies.
Brief Bioinform. 2014;16(4):563-75 - PMID: 25256289
Martin J, Hamshere ML, Stergiakouli E, O'Donovan MC, Thapar A
Neurocognitive abilities in the general population and composite genetic risk scores for attention-deficit hyperactivity disorder.
J Child Psychol Psychiatry. 2014;56(6):648-56 - PMID: 25280069 - PMCID: PMC4431584
Martin J, Hamshere ML, Stergiakouli E, O'Donovan MC, Thapar A
Genetic risk for attention-deficit/hyperactivity disorder contributes to neurodevelopmental traits in the general population.
Biol Psychiatry. 2014;76(8):664-71 - PMID: 24673882 - PMCID: PMC4183378
Martin J, Cooper M, Hamshere ML, Pocklington A, Scherer SW, Kent L, Gill M, Owen MJ, Williams N, O'Donovan MC, Thapar A, Holmans P
Biological overlap of attention-deficit/hyperactivity disorder and autism spectrum disorder: evidence from copy number variants.
J Am Acad Child Adolesc Psychiatry. 2014;53(7):761-70.e26 - PMID: 24954825 - PMCID: PMC4074351
Cooper M, Martin J, Langley K, Hamshere M, Thapar A
Autistic traits in children with ADHD index clinical and cognitive problems.
Eur Child Adolesc Psychiatry. 2013;23(1):23-34 - PMID: 23616179 - PMCID: PMC3899449
Hamshere ML, Langley K, Martin J, Agha SS, Stergiakouli E, Anney RJ, Buitelaar J, Faraone SV, Lesch KP, Neale BM, Franke B, Sonuga-Barke E, Asherson P, Merwood A, Kuntsi J, Medland SE, Ripke S, Steinhausen HC, Freitag C, Reif A, Renner TJ, Romanos M, Romanos J, Warnke A, Meyer J, Palmason H, Vasquez AA, Lambregts-Rommelse N, Roeyers H, Biederman J, Doyle AE, Hakonarson H, Rothenberger A, Banaschewski T, Oades RD, McGough JJ, Kent L, Williams N, Owen MJ, Holmans P, O'Donovan MC, Thapar A
High loading of polygenic risk for ADHD in children with comorbid aggression.
Am J Psychiatry. 2013;170(8):909-16 - PMID: 23599091 - PMCID: PMC3935265
Martin J, Hamshere ML, O'Donovan MC, Rutter M, Thapar A
Factor structure of autistic traits in children with ADHD.
J Autism Dev Disord. 2014;44(1):204-15 - PMID: 23748436 - PMCID: PMC3898364
Ahuja A, Martin J, Langley K, Thapar A
Intellectual disability in children with attention deficit hyperactivity disorder.
J Pediatr. 2013;163(3):890-5.e1 - PMID: 23608559 - PMCID: PMC4078221
Hamshere ML, Stergiakouli E, Langley K, Martin J, Holmans P, Kent L, Owen MJ, Gill M, Thapar A, O'Donovan M, Craddock N
Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia.
Br J Psychiatry. 2013;203(2):107-11 - PMID: 23703318 - PMCID: PMC3730114
Langley K, Martin J, Agha SS, Davies C, Stergiakouli E, Holmans P, Williams N, Owen M, O'Donovan M, Thapar A
Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants.
Br J Psychiatry. 2011;199(5):398-403 - PMID: 22045946 - PMCID: PMC3205349
Neale BM, Kou Y, Liu L, Ma'ayan A, Samocha KE, Sabo A, Lin CF, Stevens C, Wang LS, Makarov V, Polak P, Yoon S, Maguire J, Crawford EL, Campbell NG, Geller ET, Valladares O, Schafer C, Liu H, Zhao T, Cai G, Lihm J, Dannenfelser R, Jabado O, Peralta Z, Nagaswamy U, Muzny D, Reid JG, Newsham I, Wu Y, Lewis L, Han Y, Voight BF, Lim E, Rossin E, Kirby A, Flannick J, Fromer M, Shakir K, Fennell T, Garimella K, Banks E, Poplin R, Gabriel S, DePristo M, Wimbish JR, Boone BE, Levy SE, Betancur C, Sunyaev S, Boerwinkle E, Buxbaum JD, Cook EH, Devlin B, Gibbs RA, Roeder K, Schellenberg GD, Sutcliffe JS, Daly MJ
Patterns and rates of exonic de novo mutations in autism spectrum disorders.
Nature. 2012;485(7397):242-5 - PMID: 22495311 - PMCID: PMC3613847
Samocha KE, Lim JE, Cheng R, Sokoloff G, Palmer AA
Fine mapping of QTL for prepulse inhibition in LG/J and SM/J mice using F(2) and advanced intercross lines.
Genes Brain Behav. 2010;9(7):759-67 - PMID: 20597988 - PMCID: PMC3749925
Cheng R, Lim JE, Samocha KE, Sokoloff G, Abney M, Skol AD, Palmer AA
Genome-wide association studies and the problem of relatedness among advanced intercross lines and other highly recombinant populations.
Genetics. 2010;185(3):1033-44 - PMID: 20439773 - PMCID: PMC2907190
Norgard EA, Jarvis JP, Roseman CC, Maxwell TJ, Kenney-Hunt JP, Samocha KE, Pletscher LS, Wang B, Fawcett GL, Leatherwood CJ, Wolf JB, Cheverud JM
Replication of long-bone length QTL in the F9-F10 LG,SM advanced intercross.
Mamm Genome. 2009;20(4):224-35 - PMID: 19306044 - PMCID: PMC2736561
Kelsen D, Jhawer M, Ilson D, Tse A, Randazzo J, Robinson E, Capanu M, Shah MA
Analysis of survival with modified docetaxel, cisplatin, fluorouracil (mDCF), and bevacizumab (BEV) in patients with metastatic gastroesophageal (GE) adenocarcinoma: Results of a phase II clinical trial.
J Clin Oncol. 2009;27(15_suppl):4512 - PMID: 27962705
Koch H, Rusch W, Frühmorgen P, Lux G
[Diagnosis of acute gastrointestinal hemorrhages].
MMW Munch Med Wochenschr. 1979;121(29-30):975-6 - PMID: 111111
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