Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci.
Neuron. 2015;87(6):1215-1233 - PMID: 26402605
Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry.
Hum Mol Genet. 2015;24(16):4728-38 - PMID: 25994509 - PMCID: PMC4512626
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.
J Clin Invest. 2015;125(4):1739-51 - PMID: 25798622 - PMCID: PMC4409020
Evolutionary history inferred from the de novo assembly of a non-model organism, the blue-eyed black lemur.
Mol Ecol. 2015;:ePub - PMID: 26198179
Efficient Bayesian mixed-model analysis increases association power in large cohorts.
Nat Genet. 2015;47(3):284-90 - PMID: 25642633 - PMCID: PMC4342297
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Nat Genet. 2015;47(3):291-5 - PMID: 25642630 - PMCID: PMC4495769
The relative contribution of common and rare genetic variants to ADHD.
Transl Psychiatry. 2015;5:e506 - PMID: 25668434 - PMCID: PMC4445754
Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) traits in children and clinical ADHD.
J Am Acad Child Adolesc Psychiatry. 2015;54(4):322-7 - PMID: 25791149 - PMCID: PMC4382052
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.
Int J Epidemiol. 2015;:ePub - PMID: 26286434
The relationship between sleep quality and neurocognition in bipolar disorder.
J Affect Disord. 2015;187:156-162 - PMID: 26339925
Phenotypic extremes in rare variant study designs.
Eur J Hum Genet. 2015;:ePub - PMID: 26350511
5 year mortality predictors in 498,103 UK Biobank participants: a prospective population-based study.
Lancet. 2015;386(9993):533-40 - PMID: 26049253
Genetic research in autism spectrum disorders.
Curr Opin Pediatr. 2015;:ePub - PMID: 26371945
Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.
Int J Epidemiol. 2015;44(2):638-50 - PMID: 26050256
Partitioning heritability by functional annotation using genome-wide association summary statistics.
Nat Genet. 2015;:ePub - PMID: 26414678
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Nat Genet. 2015;:ePub - PMID: 26414677
An atlas of genetic correlations across human diseases and traits.
Nat Genet. 2015;:ePub - PMID: 26414676
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Am J Hum Genet. 2015;97(4):576-92 - PMID: 26430803
Interpreting de novo Variation in Human Disease Using denovolyzeR.
Curr Protoc Hum Genet. 2015;87:7.25.1-7.25.15 - PMID: 26439716
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.
Immunity. 2015;43(4):715-726 - PMID: 26488816
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.
Lancet. 2015;:ePub - PMID: 26490195
Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
Mol Psychiatry. 2015;:ePub - PMID: 26503763
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.
Nat Genet. 2015;:ePub - PMID: 26523775
Genetic effect of chemotherapy exposure in children of testicular cancer survivors.
Clin Cancer Res. 2015;:ePub - PMID: 26631610
Abundant contribution of short tandem repeats to gene expression variation in humans.
Nat Genet. 2015;:ePub - PMID: 26642241
2014 curt stern award: a tryst with genetics.
Am J Hum Genet. 2015;96(3):369-71 - PMID: 25748355
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways.
Nat Neurosci. 2015;:ePub - PMID: 25599223
Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci.
Nat Commun. 2015;6:5966 - PMID: 25608926
No Evidence for Association of Autism with Rare Heterozygous Point Mutations in Contactin-Associated Protein-Like 2 (CNTNAP2), or in Other Contactin-Associated Proteins or Contactins.
PLoS Genet. 2015;11(1):e1004852 - PMID: 25621974
Exome Sequencing in Suspected Monogenic Dyslipidemias.
Circ Cardiovasc Genet. 2015;:ePub - PMID: 25632026
Efficient Bayesian mixed-model analysis increases association power in large cohorts.
Nat Genet. 2015;:ePub - PMID: 25642633
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies.
Nat Genet. 2015;:ePub - PMID: 25642630
Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder.
Am J Hum Genet. 2015;:ePub - PMID: 25640677
Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy.
J Clin Invest. 2015;125(1):456-457 - PMID: 25654555
The evaluation of tools used to predict the impact of missense variants is hindered by two types of circularity.
Hum Mutat. 2015;:ePub - PMID: 25684150
Second-generation PLINK: rising to the challenge of larger and richer datasets.
Gigascience. 2015;4:7 - PMID: 25722852 - PMCID: PMC4342193
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
Nat Genet. 2015;:ePub - PMID: 25751624
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.
Nat Genet. 2015;:ePub - PMID: 25559196
Rare Genetic Variants in the CFI Gene are Associated with Advanced Age-Related Macular Degeneration and Commonly Result in Reduced Serum Factor I Levels.
Hum Mol Genet. 2015;:ePub - PMID: 25788521
The Genetics of Neuropsychiatric Diseases: Looking In and Beyond the Exome.
Annu Rev Neurosci. 2015;:ePub - PMID: 25840007
BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.
J Clin Invest. 2015;:ePub - PMID: 25938782
A Potential Contributory Role for Ciliary Dysfunction in the 16p11.2 600 kb BP4-BP5 Pathology.
Am J Hum Genet. 2015;:ePub - PMID: 25937446
Effect of predicted protein-truncating genetic variants on the human transcriptome.
Science. 2015;348(6235):666-9 - PMID: 25954003
The landscape of genomic imprinting across diverse adult human tissues.
Genome Res. 2015;:ePub - PMID: 25953952
Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.
Cell Rep. 2015;:ePub - PMID: 26095365
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Nat Genet. 2015;:ePub - PMID: 26192919
Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia.
Transl Psychiatry. 2015;5:e607 - PMID: 26196440
Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models.
J Clin Epidemiol. 2015;:ePub - PMID: 26119889
Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models.
J Clin Epidemiol. 2015;:ePub - PMID: 26119889
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